Nanomaterials targeting cancer-associated fibroblasts to overcome stromal barriers in cancer immunotherapy
Zhongsong Zhang, Rong Wang, Long Chen · 2026
Read Nanomaterials targeting cancer-associated fibroblasts to overcome stromal barriers in cancer immunotherapy by Zhongsong Zhang, Rong Wang, Long Chen (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13393494.txt.
Description
Zhongsong Zhang and co-authors review nanomaterials that target cancer-associated fibroblasts to aid immunotherapy. These fibroblasts shape the tumor setting and help cancers hide from the immune system. They also drive spread and drug resistance, yet they come in many subtypes.
The review covers fibroblast biology and how each subtype aids tumor growth. It then surveys tiny carriers built to reach and change these cells. Main tactics include reprogramming the cells and breaking down the dense matrix around tumors. Other tactics target immune checkpoints through the fibroblast route. The authors weigh gains so far and gaps that remain. The goal is a tumor setting where immune therapy can work.
Catalog record
| CREATOR | Zhongsong Zhang, Rong Wang, Long Chen |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 184 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |