Milk-derived exosome-based strategy targeting ferroptosis–glycolysis network promotes bone regeneration in diabetic aging comorbidity

Zengguang Wang, Haiyang Lin, Yuntao Li, Yiming Li, Chen Xu, Yaokai Gan · 2026

Read Milk-derived exosome-based strategy targeting ferroptosis–glycolysis network promotes bone regeneration in diabetic aging comorbidity by Zengguang Wang, Haiyang Lin, Yuntao Li, Yiming Li, Chen Xu, Yaokai Gan (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13393254.txt.

Description

Zengguang Wang and coauthors describe a 2026 experimental strategy for healing bone in people who have both diabetes and aging-related decline. Diabetes and aging together weaken bone marrow stem cells, so bone repairs poorly, and the paper traces that failure to a linked network of cell death and energy metabolism.

The team built a combined approach using tiny vesicles from milk, called exosomes, together with anaerobic exercise. The exosomes steadied a protective signal named NRF2 and curbed a damaging form of cell death called ferroptosis. For readers, the paper links a detailed molecular account to a practical repair strategy worth testing further.

Catalog record

CREATORZengguang Wang, Haiyang Lin, Yuntao Li, Yiming Li, Chen Xu, Yaokai Gan
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE72 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13393254

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