RETRACTION: Intervention Mechanism of Hunag‐Lian Jie‐Du Decoction on Canonical Wnt/β‐Catenin Signaling Pathway in Psoriasis Mouse Model
Evidence-Based Complementary and Alternative Medicine · 2026
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Description
Evidence-Based Complementary and Alternative Medicine retracts a mouse study claiming that Huang-Lian Jie-Du decoction, a classic four-herb Chinese formula, treats psoriasis by acting on the canonical Wnt and beta-catenin signalling pathway. The notice, issued in 2026 by agreement between the authors and publisher John Wiley and Sons, follows concerns raised on the PubPeer discussion site. The authors themselves asked for the retraction once the problems were laid out.
Two panels in one figure, meant to show different proteins at different formula doses, contain unexpectedly similar regions, and two protein bands in another figure, labelled as different targets, look highly alike. The authors attribute the faults to confusion while assembling figures. Because the images underpin the paper's claims about the pathway, the editors and authors agreed the record could not stand as published.
Catalog record
| CREATOR | Evidence-Based Complementary and Alternative Medicine |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 1434 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |