Segmental Absence of Intestinal Musculature in Adults: A Report of Five Cases Among 86 Intestinal Perforations

Naoko Nambu, Yuki Kubo, Tsukasa Yoshikawa, Kaito Muroki, Nobuyuki Terada, Shin-ichi Nakatsuka · 2026

Read Segmental Absence of Intestinal Musculature in Adults: A Report of Five Cases Among 86 Intestinal Perforations by Naoko Nambu, Yuki Kubo, Tsukasa Yoshikawa, Kaito Muroki, Nobuyuki Terada, Shin-ichi Nakatsuka (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13392816.txt.

Description

Naoko Nambu and five colleagues reviewed eighty-six adults operated on for a burst intestine. They hunted for cases caused by a missing stretch of gut muscle rather than by infection or blocked blood flow. Diverticular disease led the list of causes, followed by poor blood supply, with the muscle-gap condition third. Five patients in total had the rare defect, called segmental absence of intestinal musculature.

Four of the five bursts sat in the sigmoid colon and one in the caecum, and most patients were older women. Under the microscope the muscle layer stopped abruptly or thinned to nothing at the hole, without the deep infection or dead tissue that would suggest another cause. Because the condition appeared commoner than textbooks imply, the authors urge generous tissue sampling after such surgery so the diagnosis is not missed.

Catalog record

CREATORNaoko Nambu, Yuki Kubo, Tsukasa Yoshikawa, Kaito Muroki, Nobuyuki Terada, Shin-ichi Nakatsuka
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE21785
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13392816

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