Genomic epidemiology of carbapenem resistance in Acinetobacter baumannii in Chile
Pablo Araya-Vega, Maximiliano Matus-Köhler, Victoria Mardones-Verdugo, Sofía Gómez-Inostroza, Paulina González-Muñoz, Esteban Paredes-Osses, Freddy Roach-Poblete, Gerardo González-Rocha, Andrés Opazo-Capurro · 2026
Read Genomic epidemiology of carbapenem resistance in Acinetobacter baumannii in Chile by Pablo Araya-Vega, Maximiliano Matus-Köhler, Victoria Mardones-Verdugo, Sofía Gómez-Inostroza, Paulina González-Muñoz, Esteban Paredes-Osses, Freddy Roach-Poblete, Gerardo González-Rocha, Andrés Opazo-Capurro (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13392470.txt.
Description
Pablo Araya-Vega leads a genomic survey of Acinetobacter baumannii in Chile, a hospital bacterium that often shrugs off carbapenem antibiotics, the drugs kept for the hardest infections. Chilean genome data had been thin, so the team combined forty-two freshly sequenced isolates with forty-one public ones. The collection spans roughly three decades.
Typing showed a mixed population led by two related lineages within international clone four, and nearly all isolates counted as carbapenem non-susceptible. Resistance rested mainly on two OXA-type enzymes carried on plasmids that can move between bacteria, plus a common insertion next to an inbuilt OXA gene. One isolate carried the NDM-1 gene. The authors argue that tracking these mobile elements matters as much as tracking the strains themselves for hospital control.
Catalog record
| CREATOR | Pablo Araya-Vega, Maximiliano Matus-Köhler, Victoria Mardones-Verdugo, Sofía Gómez-Inostroza, Paulina González-Muñoz, Esteban Paredes-Osses, Freddy Roach-Poblete, Gerardo González-Rocha, Andrés Opazo-Capurro |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 34811 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |