Mitophagy suggesting a possible association with oocyte maturation: A study of granulosa cells from follicular fluid of normoresponder and diminished ovarian reserve cases
Çağrı Öner, Damla Kolcuoğlu, Nergis Özlem Kiliç, Defne Dumanli, Ahmet Can Çelik, Alara Kaya, Baturalp Bakirci, Sena Köstü, Ece Bilge Şimşek, Belgin Selam, Ertuğrul Çolak · 2026
Read Mitophagy suggesting a possible association with oocyte maturation: A study of granulosa cells from follicular fluid of normoresponder and diminished ovarian reserve cases by Çağrı Öner, Damla Kolcuoğlu, Nergis Özlem Kiliç, Defne Dumanli, Ahmet Can Çelik, Alara Kaya, Baturalp Bakirci, Sena Köstü, Ece Bilge Şimşek, Belgin Selam, Ertuğrul Çolak (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13392319.txt.
Description
Çağrı Öner and colleagues study, in 2026, whether a cleanup act in egg-support cells can mark egg maturity in fertility care. The act, called mitophagy, clears worn-out power units of the cell. When those units fail, egg quality can fall.
Granulosa cells from follicular fluid were collected from thirty normal responders and thirty women with diminished ovarian reserve during IVF. The team gauged genes that steer unit fusion and this cleanup. The genes were MFN-1, MFN-2, and PARKIN. Cells came from eggs at two stages of maturity. Fertility doctors gain a would-be cell marker. It could help judge an egg's worth with no harm to the egg at all.
Catalog record
| CREATOR | Çağrı Öner, Damla Kolcuoğlu, Nergis Özlem Kiliç, Defne Dumanli, Ahmet Can Çelik, Alara Kaya, Baturalp Bakirci, Sena Köstü, Ece Bilge Şimşek, Belgin Selam, Ertuğrul Çolak |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 40293 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |