Hormesis as a Geometric Necessity of Bounded Adaptive Systems: Quantitative Predictions From First Principles
Daniel John Murray · 2026
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Description
Daniel John Murray argues, in 2026, that hormesis, the beneficial response to low doses of stressors, follows necessarily from the geometry of bounded adaptive systems. Instead of fitting curves to dose data, he derives the biphasic pattern from first principles.
Bounded responses are recast in rapidity coordinates, with repair activation and damage accumulation treated as opposing bounded steps with separately measurable thresholds. The resulting predictions are compared with published dose-response data for hydrogen peroxide, cadmium chloride, and heat shock. Readers gain a theory with numbers, one that can be put to the test. The low-dose gain zone has long been told from data alone. Here its place is worked out in advance, from the shape of the system.
Catalog record
| CREATOR | Daniel John Murray |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 50151 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |