Recombinant Bombali ebolavirus in cynomolgus macaques as a survival model of Ebola virus disease
Jacquelyn Turcinovic, Karla A Fenton, Krystle N Agans, Viktoriya Borisevich, Daniel J Deer, Joan B Geisbert, Rachel O’Toole, Dafna Abelson, Natalie S Dobias, Abhishek N Prasad, Courtney Woolsey, John H Connor, César G Albariño, Thomas W Geisbert, Robert W Cross · 2026
Read Recombinant Bombali ebolavirus in cynomolgus macaques as a survival model of Ebola virus disease by Jacquelyn Turcinovic, Karla A Fenton, Krystle N Agans, Viktoriya Borisevich, Daniel J Deer, Joan B Geisbert, Rachel O’Toole, Dafna Abelson, Natalie S Dobias, Abhishek N Prasad, Courtney Woolsey, John H Connor, César G Albariño, Thomas W Geisbert, Robert W Cross (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13392047.txt.
Description
Jacquelyn Turcinovic's team tested lab-made Bombali ebolavirus in cynomolgus monkeys to gauge its human disease risk. No live virus has been isolated from bats in Sierra Leone, Kenya, Guinea, Mozambique, and Tanzania. Monkeys challenged with the lab-made clone showed hallmark Ebola traits. These included vessel leak, lymphopenia, neutrophilia, and swelling.
Virus appeared in liver, lymph nodes, and adrenal gland at peak virus load, yet all animals survived and mounted strong IgG and blocking antibody responses. Bombali virus thus looks weakened beside Ebola, Bundibugyo, Sudan, and Tai Forest viruses, and may serve as a model of resolving Ebola virus disease.
Catalog record
| CREATOR | Jacquelyn Turcinovic, Karla A Fenton, Krystle N Agans, Viktoriya Borisevich, Daniel J Deer, Joan B Geisbert, Rachel O’Toole, Dafna Abelson, Natalie S Dobias, Abhishek N Prasad, Courtney Woolsey, John H Connor, César G Albariño, Thomas W Geisbert, Robert W Cross |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 50 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |