Personalized whole-genome–based ctDNA dynamics during neoadjuvant therapy across breast cancer subtypes: results from MONITOR-Breast
Julia Foldi, Gregory Hogan, Katherine Johansen Taber, Matthew LaBella, Britney Sadler, Ravi Patel, Marija Balic, Derrick Haslem, Marcela Mazo Canola, Judy Peih-Ying Tsai, Therese Cusick, Niyati Nathwani, Yoichi Naito, Chikako Funasaka, Karlton Wong, Alexander Ham, Ashley Acevedo, CJ Battey, Genevieve M Gould, Dale Muzzey, Jeff Jasper · 2026
Read Personalized whole-genome–based ctDNA dynamics during neoadjuvant therapy across breast cancer subtypes: results from MONITOR-Breast by Julia Foldi, Gregory Hogan, Katherine Johansen Taber, Matthew LaBella, Britney Sadler, Ravi Patel, Marija Balic, Derrick Haslem, Marcela Mazo Canola, Judy Peih-Ying Tsai, Therese Cusick, Niyati Nathwani, Yoichi Naito, Chikako Funasaka, Karlton Wong, Alexander Ham, Ashley Acevedo, CJ Battey, Genevieve M Gould, Dale Muzzey, Jeff Jasper (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13390526.txt.
Description
Julia Foldi leads a 2026 prospective study tracking tumour DNA in blood during chemotherapy given before breast cancer surgery. Clearing all invasive cancer by surgery strongly predicts lower relapse risk, and blood tumour DNA may signal that response earlier.
The MONITOR-Breast study enrolled 154 patients across breast cancer subtypes and sampled blood at high frequency using an ultrasensitive residual disease test built from each patient's whole tumour genome. Earlier studies sampled less often with less sensitive tests. Oncologists gain a detailed picture of how blood signals rise and fall during treatment, a step toward using blood tests to adjust therapy before surgery rather than waiting for pathology results.
Catalog record
| CREATOR | Julia Foldi, Gregory Hogan, Katherine Johansen Taber, Matthew LaBella, Britney Sadler, Ravi Patel, Marija Balic, Derrick Haslem, Marcela Mazo Canola, Judy Peih-Ying Tsai, Therese Cusick, Niyati Nathwani, Yoichi Naito, Chikako Funasaka, Karlton Wong, Alexander Ham, Ashley Acevedo, CJ Battey, Genevieve M Gould, Dale Muzzey, Jeff Jasper |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 48973 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |