Evaluation of epithelial, stromal, and corneal thickness maps in the distinction between pellucid marginal degeneration and inferior keratoconus (pellucid-like)

Büşra Dilara Yıldırım Erdal, Burcu Kazancı · 2026

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Description

Büşra Yıldırım Erdal and Burcu Kazancı test whether thickness maps can split two look-alike corneal diseases, in a 2026 study. Pellucid marginal degeneration and a low form of keratoconus both bow the cornea's lower edge, and scans can confuse them. The team read 114 eyes with a wide-field front-eye scanner, recording thickness for three layers: the surface skin, the middle stroma, and the whole cornea.

One pattern held firm. In the degeneration group, the lowest thickness values across a ring of lower and nasal zones ran thinner than in the keratoconus group, in every layer. A single stromal gap between two zones sorted the diseases with strong accuracy. A ratio of surface values across zones did as well. The authors say layer maps from one scan can settle a diagnosis that shape alone leaves open.

Catalog record

CREATORBüşra Dilara Yıldırım Erdal, Burcu Kazancı
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE43 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13390431

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