Outcomes of Hormone receptor-positive/HER2-negative early breast cancer patients by risk of recurrence groups focusing on the intermediate-risk group: Retrospective analysis from GEICAM studies

Sonia Servitja, Eva Carrasco, Raquel Andrés, Álvaro Rodríguez-Lescure, Miguel Martín, Manuel Ruiz-Borrego, Ángel Guerrero, Begoña Bermejo, Antonio Antón, Montserrat Muñoz, Mireia Margeli, Isabel Álvarez, Luis Antonio Fernández, Jose Ponce, Josefina Cruz, Purificación Martínez, Sara López-Tarruella, · 2026

Read Outcomes of Hormone receptor-positive/HER2-negative early breast cancer patients by risk of recurrence groups focusing on the intermediate-risk group: Retrospective analysis from GEICAM studies by Sonia Servitja, Eva Carrasco, Raquel Andrés, Álvaro Rodríguez-Lescure, Miguel Martín, Manuel Ruiz-Borrego, Ángel Guerrero, Begoña Bermejo, Antonio Antón, Montserrat Muñoz, Mireia Margeli, Isabel Álvarez, Luis Antonio Fernández, Jose Ponce, Josefina Cruz, Purificación Martínez, Sara López-Tarruella, (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13390205.txt.

Description

Sonia Servitja's team analysed long-term results for 8,825 Spanish patients with hormone-sensor-positive, HER2-negative early breast cancer, grouped by relapse risk. Endocrine therapy with or without CDK4/6 inhibitors is now standard for intermediate- and high-risk disease, but real-world long-term relapse data matter for prescribing choices.

With a median follow-up near eleven years, ten-year invasive disease-free life span ran 53.8 percent in the high-risk group, 73.8 percent in the intermediate group, and 84.0 percent in the low-risk group, with overall life span following the same gradient. High-risk relapses peaked in years two to three with a second peak at year seven, sharpening the case for extended vigilance.

Catalog record

CREATORSonia Servitja, Eva Carrasco, Raquel Andrés, Álvaro Rodríguez-Lescure, Miguel Martín, Manuel Ruiz-Borrego, Ángel Guerrero, Begoña Bermejo, Antonio Antón, Montserrat Muñoz, Mireia Margeli, Isabel Álvarez, Luis Antonio Fernández, Jose Ponce, Josefina Cruz, Purificación Martínez, Sara López-Tarruella,
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE37 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13390205

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