UBTD1 Drives Ovarian Cancer Progression via Mutation‐Associated Alterations, Stromal Microenvironment Remodeling, and TNF/AP‐1 Signaling
Aixin Liu, Yanxia Chen, Xian Zhao, Junying Zhou, Guanying Feng, Huijuan Zhang, Baiyang Liu, Yongbin Chen, Cuiping Yang · 2026
Read UBTD1 Drives Ovarian Cancer Progression via Mutation‐Associated Alterations, Stromal Microenvironment Remodeling, and TNF/AP‐1 Signaling by Aixin Liu, Yanxia Chen, Xian Zhao, Junying Zhou, Guanying Feng, Huijuan Zhang, Baiyang Liu, Yongbin Chen, Cuiping Yang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13390016.txt.
Description
Aixin Liu and colleagues investigate, in 2026, a protein called UBTD1 that may drive ovarian cancer growth. Ovarian cancer is often found late, spreads readily, and resists platinum drugs, so new drivers of the disease are urgently sought.
The team blends single-cell gene data, mutation analysis, and immune environment checks from public databases such as The Cancer Genome Atlas. They link UBTD1 to mutation-related change and to reshaping of the tissue around tumours. A TNF and AP-1 signalling route is also implicated. Laboratory checks support the database findings. Cancer researchers gain a candidate target with a mapped mechanism, plus a worked example of joining public data with bench tests to judge a gene's role.
Catalog record
| CREATOR | Aixin Liu, Yanxia Chen, Xian Zhao, Junying Zhou, Guanying Feng, Huijuan Zhang, Baiyang Liu, Yongbin Chen, Cuiping Yang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 54498 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |