Risk factors and critical thresholds for glucocorticoid-induced ocular adverse reactions in children: implications for muscle and neuromuscular disease management
You Li, Tingxin Cui, Zhilang Lin, Lanqin Zhao, Yunxi Lai, Dongyuan Yun, Zikai Lin, Mingyuan Li, Yunjian Huang, Shiyuan Chen, Dongni Wang, Yuanquan Qiu, Yuanyuan Xu, Yahan Yang, Duoru Lin, Xiaoyun Jiang, Haotian Lin · 2026
Read Risk factors and critical thresholds for glucocorticoid-induced ocular adverse reactions in children: implications for muscle and neuromuscular disease management by You Li, Tingxin Cui, Zhilang Lin, Lanqin Zhao, Yunxi Lai, Dongyuan Yun, Zikai Lin, Mingyuan Li, Yunjian Huang, Shiyuan Chen, Dongni Wang, Yuanquan Qiu, Yuanyuan Xu, Yahan Yang, Duoru Lin, Xiaoyun Jiang, Haotian Lin (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13389614.txt.
Description
You Li's team searched for risk factors and dose thresholds for eye damage from steroid therapy in children, looking at lens clouding and steroid-induced eye pressure rise. Steroids are key for childhood muscle and nerve-muscle disease, but long use can cause lasting vision loss.
In a case-control study of 305 children with kidney disease treated between December 2020 and December 2022, seven factors model rear under-capsule lens clouding. These were younger age, longer treatment, high blood pressure, growth delay, vitamin D shortage, immune drug use, and oral methylprednisolone. Lens-clouding risk rose past about five and a half months or a total dose near 5,888 milligrams, while higher daily dose flagged pressure rise.
Catalog record
| CREATOR | You Li, Tingxin Cui, Zhilang Lin, Lanqin Zhao, Yunxi Lai, Dongyuan Yun, Zikai Lin, Mingyuan Li, Yunjian Huang, Shiyuan Chen, Dongni Wang, Yuanquan Qiu, Yuanyuan Xu, Yahan Yang, Duoru Lin, Xiaoyun Jiang, Haotian Lin |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 27 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |