Highly dynamic assemblies of glycolytic enzymes by quinary determinants
Blanca Poquet, Galal Yahya, Laia Ferrer, Enrique Marcos, Carme Gallego, Martí Aldea · 2026
Read Highly dynamic assemblies of glycolytic enzymes by quinary determinants by Blanca Poquet, Galal Yahya, Laia Ferrer, Enrique Marcos, Carme Gallego, Martí Aldea (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13389168.txt.
Description
Blanca Poquet's team found that the enzymes of glycolysis, the cell's main sugar-breaking pathway, gather in fleeting clusters they call protein flocks. Whether sequential enzymes truly channel molecules between them has long been debated, and the workings behind any such clustering was unknown.
Using correlation spectroscopy and proximity labelling in yeast and human cells, the team saw assemblies lasting under ten milliseconds, tied to matching surface chemistry across glycolytic enzymes. These quinary traits may raise efficiency and specificity while keeping toxic intermediates low, a benefit that matters most in human cells.
Catalog record
| CREATOR | Blanca Poquet, Galal Yahya, Laia Ferrer, Enrique Marcos, Carme Gallego, Martí Aldea |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 57 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |