SARS-CoV-2 infection and vaccination elicit distinct pharyngeal mucosal B cell responses in children
Qin Xu, Lihong Shi, Liya Wang, Liya Wang, Foo Cheung, Aparna Kotekar, Galina Koroleva, Elizabeth Rice, Richard Apps, Justin Lack, Craig Martens, Iyadh Douagi, Can Liu, Juraj Kabat, Hengameh Behzadpour, Lela Kardava, Tovah E. Markowitz, Margery Smelkinson, Kenneth B. Hoehn, Clarisa M. Buckner, Domini · 2026
Read SARS-CoV-2 infection and vaccination elicit distinct pharyngeal mucosal B cell responses in children by Qin Xu, Lihong Shi, Liya Wang, Liya Wang, Foo Cheung, Aparna Kotekar, Galina Koroleva, Elizabeth Rice, Richard Apps, Justin Lack, Craig Martens, Iyadh Douagi, Can Liu, Juraj Kabat, Hengameh Behzadpour, Lela Kardava, Tovah E. Markowitz, Margery Smelkinson, Kenneth B. Hoehn, Clarisa M. Buckner, Domini (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13388998.txt.
Description
Qin Xu's team weighed how children's throat immune tissues respond to SARS-CoV-2 illness versus mRNA shots, studying tonsils, adenoids, and blood. Mucosal defences guard the airways, but most vaccine studies draw blood alone, leaving tissue memory poorly mapped.
Both routes made switched memory B cells in throat tissues and blood, yet illness yielded more IgA-bearing and CXCR3-bearing memory cells, which grew more, placed distinctly, and leaned toward becoming antibody factories. Lasting activation of helper cells accompanied the illness pattern, hinting illness and shots build differently flavoured local defences.
Catalog record
| CREATOR | Qin Xu, Lihong Shi, Liya Wang, Liya Wang, Foo Cheung, Aparna Kotekar, Galina Koroleva, Elizabeth Rice, Richard Apps, Justin Lack, Craig Martens, Iyadh Douagi, Can Liu, Juraj Kabat, Hengameh Behzadpour, Lela Kardava, Tovah E. Markowitz, Margery Smelkinson, Kenneth B. Hoehn, Clarisa M. Buckner, Domini |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 131 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |