Shotgun Metagenomic Profiling of the Gut Virome in Prodromal and Confirmed Parkinson's Disease
Deepika Dinesh, Xochitl C Morgan, Jordan Jensen, Kjetil Bjornevik, Michael A Schwarzschild, Alberto Ascherio, Curtis Huttenhower, Natalia Palacios · 2026
Read Shotgun Metagenomic Profiling of the Gut Virome in Prodromal and Confirmed Parkinson's Disease by Deepika Dinesh, Xochitl C Morgan, Jordan Jensen, Kjetil Bjornevik, Michael A Schwarzschild, Alberto Ascherio, Curtis Huttenhower, Natalia Palacios (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13388000.txt.
Description
Deepika Dinesh's team asked whether the gut's viruses, mostly viruses that infect bacteria, differ in Parkinson's disease and in its prodromal phase, the period before diagnosis. They drew on two long-running health studies and applied a new profiling tool to stool samples from 62 patients, 90 prodromal people, and 123 healthy controls.
Three viral genome groups ran higher in Parkinson's and one ran lower, with the same pattern showing up before diagnosis. The authors present the gut virome as a possible early marker of the disease, while noting that this first mapping still needs testing in larger groups before any medical use.
Catalog record
| CREATOR | Deepika Dinesh, Xochitl C Morgan, Jordan Jensen, Kjetil Bjornevik, Michael A Schwarzschild, Alberto Ascherio, Curtis Huttenhower, Natalia Palacios |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 21 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |