Severe Pneumococcal Meningitis With Intracranial Hypertension and Cerebral Venous Sinus Thrombosis in a Patient With HIV and Prior Splenectomy
Omar Horani, Sarmed Mansur, Stephen Grider, Hani Saad · 2026
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Description
Omar Horani and colleagues report pneumococcal meningitis with twin brain complications in a high-risk patient in a 2026 case report. A 45-year-old man with HIV and a prior spleen removal arrived with vomiting, diarrhea, confusion, and worsening headache. His HIV was treated, with immune counts preserved, yet the encapsulated bacterium still broke through.
He developed dangerous pressure inside the skull, needing a drain, plus extensive clotting in the brain's venous sinuses. The authors stress that spleen loss cripples antibody defense against coated bacteria even when other immunity looks intact. Fast recognition and pressure control anchor their management message.
Catalog record
| CREATOR | Omar Horani, Sarmed Mansur, Stephen Grider, Hani Saad |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 13039 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |