Proteomic screening identifies HNRNPA2B1 as an epigenetic repressor of Epstein-Barr virus reactivation
Febri Gunawan Sugiokto, Yuxin Liu, Renfeng Li · 2026
Read Proteomic screening identifies HNRNPA2B1 as an epigenetic repressor of Epstein-Barr virus reactivation by Febri Gunawan Sugiokto, Yuxin Liu, Renfeng Li (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13386990.txt.
Description
Febri Gunawan Sugiokto, Yuxin Liu, and Renfeng Li hunted in two thousand twenty-six for host proteins that keep Epstein-Barr virus asleep. The virus infects nearly everyone for life, hiding quietly and waking at times through two early genes. Using a guided DNA-pull-down method with mass measurement, they listed proteins sitting on one wake-up gene's switch.
One protein stood out and proved to hold the virus down. Removing it raised wake-up gene activity, drew in the gene-reading machinery, and pushed more cells into active virus production across several cancer cell models. Virologists gain a named guardian of viral sleep and a possible drug angle.
Catalog record
| CREATOR | Febri Gunawan Sugiokto, Yuxin Liu, Renfeng Li |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 66 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |