Adjunctive probiotic therapy enhances metronidazole efficacy in bacterial vaginitis: a clinical trial on Iranian women
Zahra Vahedpoor, Parisa Mamivand, Mohammad Javad Azadchehr, Mehdi Nazeri · 2026
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Description
Zahra Vahedpoor's team tested adding a vaginal probiotic to metronidazole for bacterial vaginosis, in a 2026 trial in Iran. The double-blind, placebo trial joined 121 married women aged 18 to 48 with BV. One group got 7 days of oral metronidazole plus vaginal L. plantarum 299v for 21 days, while the other got the drug plus placebo.
Adding the live culture clearly reduced BV return versus the drug alone. The pairing was bore well with no serious adverse events reported. The authors call vaginal probiotics a hopeful adjunct therapy, while noting further studies must confirm findings and pin down optimal strains and doses.
Catalog record
| CREATOR | Zahra Vahedpoor, Parisa Mamivand, Mohammad Javad Azadchehr, Mehdi Nazeri |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 27 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |