Cellular-Level Characterization of Cone Photoreceptors and Retinal Pigment Epithelium in Stargardt Disease with Adaptive Optics Imaging
Masakazu Hiraoka, Leandre Fura, Marika Hirota, Kiyoko Gocho, Natsuko Nakamura, Satoshi Yokota, Yasuhiko Hirami, Masayo Takahashi, Shuhei Kimura, Michiko Mandai, Yasuo Kurimoto, Akiko Maeda · 2026
Read Cellular-Level Characterization of Cone Photoreceptors and Retinal Pigment Epithelium in Stargardt Disease with Adaptive Optics Imaging by Masakazu Hiraoka, Leandre Fura, Marika Hirota, Kiyoko Gocho, Natsuko Nakamura, Satoshi Yokota, Yasuhiko Hirami, Masayo Takahashi, Shuhei Kimura, Michiko Mandai, Yasuo Kurimoto, Akiko Maeda (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13383215.txt.
Description
Masakazu Hiraoka and colleagues image living eye cells at fine detail in Stargardt disease in a 2026 case series. Stargardt disease damages the light-sensing cone cells and the support layer beneath them. Using two adaptive optics methods together, the team viewed both cell types at once in the same eye regions.
Images showed uneven damage across patients and across spots in the same retina. In cases open to counting, cone density fell sharply while support cell density stayed near the normal range. The authors present the paired imaging as a feasible way to track cell-level change, which could help judge future treatments.
Catalog record
| CREATOR | Masakazu Hiraoka, Leandre Fura, Marika Hirota, Kiyoko Gocho, Natsuko Nakamura, Satoshi Yokota, Yasuhiko Hirami, Masayo Takahashi, Shuhei Kimura, Michiko Mandai, Yasuo Kurimoto, Akiko Maeda |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 39574 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |