Action and rest tremor map to distinct networks within the primary motor cortex
Lukas L. Goede, Patricia Zvarova, Savir Madan, Bassam Al-Fatly, Xin Xu, Zhipei Ling, Chen Yao, Martin Reich, Jens Volkmann, Calvin Howard, Andrea A. Kühn, Michael D. Fox, Andreas Horn · 2026
Read Action and rest tremor map to distinct networks within the primary motor cortex by Lukas L. Goede, Patricia Zvarova, Savir Madan, Bassam Al-Fatly, Xin Xu, Zhipei Ling, Chen Yao, Martin Reich, Jens Volkmann, Calvin Howard, Andrea A. Kühn, Michael D. Fox, Andreas Horn (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13382931.txt.
Description
Lukas Goede's team mapped action and rest tremor to distinct motor cortex networks, in a 2026 brain stimulation study. Both Parkinson disease and essential tremor respond to deep brain stimulation, yet whether the two tremor types share a target was unclear. The team used stimulation network mapping across patient cohorts and targets.
Rest tremor linked more strongly to effector-specific zones along the motor strip, while action tremor favored inter-effector territories, in both disorders. Clinical programming choices aligned with symptom-specific engagement. The split supports tailoring stimulation to the tremor type rather than aiming at one generic motor target.
Catalog record
| CREATOR | Lukas L. Goede, Patricia Zvarova, Savir Madan, Bassam Al-Fatly, Xin Xu, Zhipei Ling, Chen Yao, Martin Reich, Jens Volkmann, Calvin Howard, Andrea A. Kühn, Michael D. Fox, Andreas Horn |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 32 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |