Flowing Fistulas: Update on Strategies to Maintain Arteriovenous Fistula Patency

Maddison Taylor, Benjamin Lazarus · 2026

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Description

Taylor and colleagues review strategies for keeping arteriovenous fistulas open, in 2026 vascular research for dialysis patients. A fistula, a joined artery and vein in the arm, is the preferred dialysis access, yet it often narrows and fails. The chief culprit is neointimal hyperplasia, inward wall thickening driven by needle sticks, shear stress, and the inflammatory chemistry of kidney failure. The authors note it contributes to over 60 percent of dysfunctional fistulas in the literature.

Balloon angioplasty, first used for stenosis in 1982, remains the first-line rescue, forcibly dilating the narrowed segment to remodel it outward. The review weighs drug-coated balloons, stents, surgical revision, and surveillance for catching stenosis before thrombosis closes the vessel, plus the biology that makes each succeed or fail. Taylor argues durable patency needs both mechanical fixes and control of the wall's fibrotic response, since dilation alone invites the hyperplasia to return at the site.

Catalog record

CREATORMaddison Taylor, Benjamin Lazarus
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE22 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13382503

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