Unifying and unique roles of non-coding RNA biomarkers in liver and heart fibrosis

Veronika Boichenko, Svetlana Frolova, Christine Voellenkle, Germana Zaccagnini, Paolo Ferrero, Pier Paolo Bassareo, Giovanni Battista Luciani, Julia Gorelik, Fabio Martelli · 2026

Read Unifying and unique roles of non-coding RNA biomarkers in liver and heart fibrosis by Veronika Boichenko, Svetlana Frolova, Christine Voellenkle, Germana Zaccagnini, Paolo Ferrero, Pier Paolo Bassareo, Giovanni Battista Luciani, Julia Gorelik, Fabio Martelli (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13380601.txt.

Description

Veronika Boichenko and colleagues present a 2026 review of small RNA molecules that help control scarring in the liver and the heart. Scarring, called fibrosis, stiffens both organs and drives long-term failure. It involves activated support cells, excess scaffolding material, and inflammation in each organ.

The review compares three families of non-coding RNAs, which regulate genes without building proteins. Some of them act alike in liver and heart, switching the same scarring pathways up or down. Others behave differently depending on the organ. Because these molecules also circulate in the blood inside tiny parcels, they may serve as low-burden test markers. The comparison highlights shared drug targets across both organs.

Catalog record

CREATORVeronika Boichenko, Svetlana Frolova, Christine Voellenkle, Germana Zaccagnini, Paolo Ferrero, Pier Paolo Bassareo, Giovanni Battista Luciani, Julia Gorelik, Fabio Martelli
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE105568
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13380601

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