Keratins coordinate tissue spreading by balancing spreading forces with tissue material properties
Suyash Naik, Yann-Edwin Keta, Kornelija Pranjic-Ferscha, Édouard Hannezo, Silke Henkes, Carl-Philipp Heisenberg · 2026
Read Keratins coordinate tissue spreading by balancing spreading forces with tissue material properties by Suyash Naik, Yann-Edwin Keta, Kornelija Pranjic-Ferscha, Édouard Hannezo, Silke Henkes, Carl-Philipp Heisenberg (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13377027.txt.
Description
Suyash Naik and five co-authors published a developmental biology study in twenty twenty-six on how keratin fibers keep a spreading tissue from tearing itself apart. In zebrafish embryos, a cell sheet must stretch over the yolk while staying whole. Flexibility and toughness have to stay in balance.
Watching the sheet expand in living embryos, the team saw stress itself prompting the keratin network to mature. That maturation made the tissue more viscous, resisting rupture. Keratin in the yolk cell was also needed for the contractile machinery that pulls the sheet along. Genetic interference and tissue mechanics, backed by a computer model, confirmed the double role. Keratins thus tune both the pulling force and the resistance to it.
Catalog record
| CREATOR | Suyash Naik, Yann-Edwin Keta, Kornelija Pranjic-Ferscha, Édouard Hannezo, Silke Henkes, Carl-Philipp Heisenberg |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 142 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |