Arginine protects against colonic barrier injury induced by long-term peritoneal dialysis
Junhao Dai, Yongmei Zhang, Jiaqi He, Fangping Li, Hong Xin, Xuemei Zhang, Hui Yan, Yinhang Wang · 2026
Read Arginine protects against colonic barrier injury induced by long-term peritoneal dialysis by Junhao Dai, Yongmei Zhang, Jiaqi He, Fangping Li, Hong Xin, Xuemei Zhang, Hui Yan, Yinhang Wang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13376615.txt.
Description
Junhao Dai and co-authors present a 2026 journal article on colon damage from long-term peritoneal dialysis and a possible rescue by arginine. Dialysis fluid over time harms the colon's barrier, but the chemistry was unclear. The team profiled colon chemistry in mice on long dialysis treatment and found the arginine pathway sharply disturbed.
Colon arginine fell, one building enzyme dropped, and a breaking enzyme rose. Adding arginine back, in colon cells and in treated mice, restored tissue shape and the tight junction proteins that seal the barrier. The authors present arginine supply as a candidate therapy for dialysis-linked gut injury.
Catalog record
| CREATOR | Junhao Dai, Yongmei Zhang, Jiaqi He, Fangping Li, Hong Xin, Xuemei Zhang, Hui Yan, Yinhang Wang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 36 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |