Regulatory mechanisms of LGR4 on cancer and cancer stem cell properties
Jialei Yang, Jinye Zhao, Houchang Liu, Saili Luo, Jialun Hu, Yunhua Pan · 2026
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Description
Jialei Yang and five co-workers wrote a 2026 review on a receptor called LGR4 and its role in cancer. The receptor answers several signal molecules and helps organs grow and stay in repair. It acts mainly through a well-known growth path. In tumors, it shows up across many cancer types.
The review covers how much of the receptor tumors hold and what it does there. It tracks the signal paths the receptor controls in cancer cells. A key theme is cancer stem cells: the receptor helps them renew and keep their stem traits. That role also links to resistance against chemo drugs.
Catalog record
| CREATOR | Jialei Yang, Jinye Zhao, Houchang Liu, Saili Luo, Jialun Hu, Yunhua Pan |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 42 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |