Functional brain abnormalities in patients with somatic symptom disorder presenting with chest pain: a resting-state fMRI study
Yi-Fan Ding, Ke-Ying Wang, Ting Yang, Xue-Fei Liu, Ying Li, Hai-Feng Shi, Jin-Wei Qiang · 2026
Read Functional brain abnormalities in patients with somatic symptom disorder presenting with chest pain: a resting-state fMRI study by Yi-Fan Ding, Ke-Ying Wang, Ting Yang, Xue-Fei Liu, Ying Li, Hai-Feng Shi, Jin-Wei Qiang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13376194.txt.
Description
Yi-Fan Ding and her six co-authors, publishing in 2026, scan the resting brains of people whose chest pain has no physical explanation. The condition, somatic symptom disorder, brings persistent bodily symptoms that tests cannot account for. The team recruited 56 patients whose main complaint was chest pain and 46 healthy controls. Everyone received brain imaging, including scans of spontaneous activity at rest.
Patients scored far higher on symptom, anxiety, and depression scales, as expected. Their resting brain activity differed in a telling pattern. Regions for emotion control and self-reflection ran hot, while the hippocampus and insula, tied to memory and body sensing, ran quiet. The size of these shifts tracked how severe the symptoms were. The authors offer the map as a step toward understanding the disorder's brain basis and toward targets for treatment.
Catalog record
| CREATOR | Yi-Fan Ding, Ke-Ying Wang, Ting Yang, Xue-Fei Liu, Ying Li, Hai-Feng Shi, Jin-Wei Qiang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 36 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |