Is BMP-7 a promising diagnostic and prognostic biomarker for pediatric obstructive uropathy?

Mehdi Shirazi, Seyed Hossein Hosseini, Maryam Salehi, Sania Shirazi · 2026

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Description

Mehdi Shirazi and co-authors test a blood and urine marker in a 2026 study on blocked urinary flow in children. Blockage is a major cause of lasting kidney disease in childhood. Doctors still lack a reliable sign that shows who will worsen or recover.

A protein called BMP-7, known to fight scarring and protect kidneys, was measured in 200 sick children and 200 healthy controls. Levels were taken before surgery and again three months after. Block types covered joints at the kidney and bladder ends and a valve problem in boys. The study weighs whether the marker can flag the disease and forecast its course.

Catalog record

CREATORMehdi Shirazi, Seyed Hossein Hosseini, Maryam Salehi, Sania Shirazi
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE36 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13371716

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