Development and internal validation of the CLIP-M score for advanced mucosal malignant melanoma: exploratory prognostic stratification and comparative assessment with the RMH score
Burak Pacaci, Buket Erkan Ozmarasali, Adem Deligonul, Ali Fuat Gurbuz, Melek Karakurt Eryilmaz, Suheda Atas Ipek, Nisanur Sariyar Busery, Emre Yilmaz, Mustafa Alperen Tunc, Ali Kaan Guren, Erkam Kocaaslan, Ahmet Demirel, Firat Akagunduz, Nazim Can Demircan, Osman Kostek · 2026
Read Development and internal validation of the CLIP-M score for advanced mucosal malignant melanoma: exploratory prognostic stratification and comparative assessment with the RMH score by Burak Pacaci, Buket Erkan Ozmarasali, Adem Deligonul, Ali Fuat Gurbuz, Melek Karakurt Eryilmaz, Suheda Atas Ipek, Nisanur Sariyar Busery, Emre Yilmaz, Mustafa Alperen Tunc, Ali Kaan Guren, Erkam Kocaaslan, Ahmet Demirel, Firat Akagunduz, Nazim Can Demircan, Osman Kostek (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13371654.txt.
Description
Burak Pacaci and fourteen co-authors build a prognostic score for advanced mucosal melanoma, a rare and aggressive cancer of the body's inner linings, in this 2026 study. The standard Royal Marsden score was designed for cancers generally and is barely tested in this disease. Clinicians need a sharper way to tell who will do poorly.
Their CLIP-M score, fitted on eighty patients from several centers, combines three pretreatment facts: a high blood inflammation index, age sixty-five or over, and a primary site outside the head and neck. It separated patients starkly: low-risk patients lived a median of about twenty-five months, high-risk about six. Across one, two, and three years its discrimination numbers beat the older score's, though after statistical correction and internal validation the advantage rated exploratory and moderate. The authors require outside validation before clinical use.
Catalog record
| CREATOR | Burak Pacaci, Buket Erkan Ozmarasali, Adem Deligonul, Ali Fuat Gurbuz, Melek Karakurt Eryilmaz, Suheda Atas Ipek, Nisanur Sariyar Busery, Emre Yilmaz, Mustafa Alperen Tunc, Ali Kaan Guren, Erkam Kocaaslan, Ahmet Demirel, Firat Akagunduz, Nazim Can Demircan, Osman Kostek |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 55 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |