Sex-specific associations between pregnancy zone protein and acute coronary syndrome: a case-control study
Xinxin Shen, Xiaobin Guo, Ting Yang, Kaifang Yang, Weilin Wang, Huimin Chen, Fengling Lai, Mingjun Zhang, Yan Zheng, Guohai Su, Keqing Hu, Rong Huang · 2026
Read Sex-specific associations between pregnancy zone protein and acute coronary syndrome: a case-control study by Xinxin Shen, Xiaobin Guo, Ting Yang, Kaifang Yang, Weilin Wang, Huimin Chen, Fengling Lai, Mingjun Zhang, Yan Zheng, Guohai Su, Keqing Hu, Rong Huang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13371182.txt.
Description
Xinxin Shen and a large team of co-authors published this 2026 case-control study on a little-known blood protein and sudden heart trouble. Pregnancy zone protein helps manage energy, clot breakdown, and immune tuning, yet its link to acute coronary syndrome, and whether that link differs by sex, was murky. The team recruited heart patients and healthy controls at one hospital.
In all, 1,170 people took part: 721 men and 449 women. The level of the protein differed sharply by sex, with a median near 3.46 in women against 0.26 in men. Among men, patients ran higher than controls. The team modeled the tie between the protein and the syndrome while adjusting for other causes. Sex, they conclude, must be built into any reading of this marker.
Catalog record
| CREATOR | Xinxin Shen, Xiaobin Guo, Ting Yang, Kaifang Yang, Weilin Wang, Huimin Chen, Fengling Lai, Mingjun Zhang, Yan Zheng, Guohai Su, Keqing Hu, Rong Huang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 52 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |