The impact of pregestational stress on neurodevelopment: Implications for autism spectrum disorder and attention‐deficit/hyperactivity disorder
Samaneh Ahmadian‐Moghadam, Ehsan Saboory, Shiva Roshan‐Milani · 2026
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Description
Samaneh Ahmadian-Moghadam and colleagues review how stress before conception may shape child brain development in a 2026 paper. The focus is on two conditions, autism and attention deficit hyperactivity disorder, and on whether risk can be set before pregnancy begins. Human and animal studies were gathered and compared.
The review finds that stress before conception can alter chemical marks on genes in reproductive cells, shift early development of the calming GABA system, and reset the body's stress hormone axis. Those shifts may change how the fetal brain matures. The authors argue that the months before conception deserve more attention in prevention, alongside the far better studied months of pregnancy itself.
Catalog record
| CREATOR | Samaneh Ahmadian‐Moghadam, Ehsan Saboory, Shiva Roshan‐Milani |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 58 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |