The relationship between objective and subjective cognitive performance and clinical and MRI disease burden in early multiple sclerosis
Delphine Van Laethem, Lars Costers, Augusto Miravalle, Enrique Alvarez, Bennett Myers, Aaron Boster, Hanan Al Halawani, Maarten Dewil, Melissa Cambron, Matthias Grothe, Stijn Denissen, Rebecca Bartz, Diana Sima, Annemie Ribbens, Dirk Smeets, Guy Nagels · 2026
Read The relationship between objective and subjective cognitive performance and clinical and MRI disease burden in early multiple sclerosis by Delphine Van Laethem, Lars Costers, Augusto Miravalle, Enrique Alvarez, Bennett Myers, Aaron Boster, Hanan Al Halawani, Maarten Dewil, Melissa Cambron, Matthias Grothe, Stijn Denissen, Rebecca Bartz, Diana Sima, Annemie Ribbens, Dirk Smeets, Guy Nagels (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13370009.txt.
Description
Delphine Van Laethem and co-authors compare felt and measured thinking problems in early multiple sclerosis. Their 2026 study enrolled two hundred five patients diagnosed within the last fifteen years. Patients' own sense of their cognition is known to track their test scores weakly, while hugging depression much more tightly.
A phone-based symbol test supplied the objective score, and standard scales captured symptoms, mood, and fatigue. The two kinds of performance correlated only weakly. Feeling cognitively poor rode with pain, dizziness, fatigue, and low mood. Scoring poorly rode with walking trouble and with a smaller thalamus on brain scans, available for fifty-two patients. Felt performance matched no brain volume at all. The authors urge clinics to treat the two complaints as different signals.
Catalog record
| CREATOR | Delphine Van Laethem, Lars Costers, Augusto Miravalle, Enrique Alvarez, Bennett Myers, Aaron Boster, Hanan Al Halawani, Maarten Dewil, Melissa Cambron, Matthias Grothe, Stijn Denissen, Rebecca Bartz, Diana Sima, Annemie Ribbens, Dirk Smeets, Guy Nagels |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 36 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |