Effect of intrasphincteric botulinum toxin on postoperative urinary retention following stapled hemorrhoidopexy: a randomized, double-blind, placebo-controlled trial
Mina Alvandipour, Sina Safari, Maryam Vahidpoor, Ava Ranjbar, Mehdi Karimi · 2026
Read Effect of intrasphincteric botulinum toxin on postoperative urinary retention following stapled hemorrhoidopexy: a randomized, double-blind, placebo-controlled trial by Mina Alvandipour, Sina Safari, Maryam Vahidpoor, Ava Ranjbar, Mehdi Karimi (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13369158.txt.
Description
Mina Alvandipour and four co-authors test whether a botulinum toxin injection during hemorrhoid surgery can prevent a common problem: patients unable to pass urine afterward. The stapled operation studied often leaves patients needing a catheter and a longer stay. The toxin relaxes the internal anal sphincter, which the team hoped would ease the urinary block as a side benefit. Sixty-eight adults with advanced hemorrhoids joined the trial at two hospitals.
Half received the toxin during surgery and half a dummy injection, with neither side knowing which. Retention struck about forty-four percent of patients overall, but the split was stark: about twenty-one percent in the toxin group against sixty-eight percent in the dummy group. Bleeding and gas leakage did not differ between groups. The authors, who analyzed data from a trial first built to study pain, call the injection an effective guard against this complication.
Catalog record
| CREATOR | Mina Alvandipour, Sina Safari, Maryam Vahidpoor, Ava Ranjbar, Mehdi Karimi |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 33 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |