LKB1 attenuates the transport activity of GLUT1 by regulating the alternative splicing of PKM1/PKM2 in cervical cancer
Mingzhe Wu, Yaoxing Guo, Jinghua Yang, Enhua Wang, Hong-Tao Xu, Guang-Ping Wu, Huanyu Zhao · 2026
Read LKB1 attenuates the transport activity of GLUT1 by regulating the alternative splicing of PKM1/PKM2 in cervical cancer by Mingzhe Wu, Yaoxing Guo, Jinghua Yang, Enhua Wang, Hong-Tao Xu, Guang-Ping Wu, Huanyu Zhao (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13365726.txt.
Description
Mingzhe Wu and co-workers map in 2026 how a guard gene reins in sugar flow in cervix cancer cells. The guard, named LKB1, runs low in tumor flesh next to near well flesh. It steers which form of a sugar burn enzyme the cell makes, by a splice choice in its code.
More guard cuts the harsh enzyme form, a growth cue, and the sugar gate on the cell skin. Less enzyme or cue also cuts sugar take in. The guard works through a known cell fuel path. The chain marks fresh aims to starve these tumors.
Catalog record
| CREATOR | Mingzhe Wu, Yaoxing Guo, Jinghua Yang, Enhua Wang, Hong-Tao Xu, Guang-Ping Wu, Huanyu Zhao |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 31237 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |