Lonicerae japonicae flos Polyphenols Attenuate Inflammation-Related Ferroptosis and Gut Microbiota Dysbiosis in LPS-Induced Acute Lung Injury in Mice
Yingjian Guo, Chuangchuang Wang, Hongjing Dong, Tao Li, Chuanzhi Kang, Xiao Wang, Jinqian Yu · 2026
Read Lonicerae japonicae flos Polyphenols Attenuate Inflammation-Related Ferroptosis and Gut Microbiota Dysbiosis in LPS-Induced Acute Lung Injury in Mice by Yingjian Guo, Chuangchuang Wang, Hongjing Dong, Tao Li, Chuanzhi Kang, Xiao Wang, Jinqian Yu (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13363504.txt.
Description
Yingjian Guo and colleagues report a 2026 mouse study on honeysuckle flower polyphenols against acute lung injury, a sudden, severe lung failure with few safe treatments. Mice were dosed for a week before a lung irritant triggered the injury, and some groups got fecal transplants from treated mice to test whether gut microbes carried part of the benefit. Lung tissue proteins and gut microbe mixes were read in depth.
The polyphenols eased lung damage, calmed the master swelling switch in lung cells, and raised antioxidant defenses, which curbed a rust-like cell death called ferroptosis. Gut microbes shifted toward helpful kinds that make protective fatty acids. Transplants alone also eased lung and gut harm, showing the gut-lung link shares the credit.
Catalog record
| CREATOR | Yingjian Guo, Chuangchuang Wang, Hongjing Dong, Tao Li, Chuanzhi Kang, Xiao Wang, Jinqian Yu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 33231 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |