Integrated Histopathologic and Targeted Genomic Characterization of Gastric Adenocarcinomas with Yolk Sac Tumor Differentiation
Annabella Di Mauro, Rosalia Anna Rega, Rosalinda Sorrentino, Anna Falanga, Maddalena Leongito, Vittorio Albino, Andrea Belli, Imma D’Arbitrio, Saverio Simonelli, Rossella De Cecio, Salvatore Tafuto, Guglielmo Nasti, Alessandro Ottaiano, Fabiana Tatangelo · 2026
Read Integrated Histopathologic and Targeted Genomic Characterization of Gastric Adenocarcinomas with Yolk Sac Tumor Differentiation by Annabella Di Mauro, Rosalia Anna Rega, Rosalinda Sorrentino, Anna Falanga, Maddalena Leongito, Vittorio Albino, Andrea Belli, Imma D’Arbitrio, Saverio Simonelli, Rossella De Cecio, Salvatore Tafuto, Guglielmo Nasti, Alessandro Ottaiano, Fabiana Tatangelo (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13362424.txt.
Description
Annabella Di Mauro and a large team present a 2026 study of three stomach cancers that partly grew like yolk sac tumors, a rare and odd pattern. Such mixed growth hints that stomach cancer cells can shift into a more fetal-like form. The team studied tumor tissue under the microscope and ran a wide gene test on all three cases at one cancer center.
All three tumors mixed standard stomach cancer tissue with fetal-type areas that made fetal proteins. Gene tests showed stable DNA, a mid-level load of mutations, and changes in growth pathways shared with other gut cancers. Repeated changes hit genes named CCND3 and MDM2. With only three cases, the authors call for larger studies to pin down how this rare form arises.
Catalog record
| CREATOR | Annabella Di Mauro, Rosalia Anna Rega, Rosalinda Sorrentino, Anna Falanga, Maddalena Leongito, Vittorio Albino, Andrea Belli, Imma D’Arbitrio, Saverio Simonelli, Rossella De Cecio, Salvatore Tafuto, Guglielmo Nasti, Alessandro Ottaiano, Fabiana Tatangelo |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 33192 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |