Neurodevelopmental and Behavioral Profiles in Children with Tuberous Sclerosis Complex: Exploratory Associations with Epilepsy Onset and Cortical Tuber Burden
Rui Carlos Silva, Tiago S. Bara, Daniel A. do Valle, Mara L. Cordeiro · 2026
Read Neurodevelopmental and Behavioral Profiles in Children with Tuberous Sclerosis Complex: Exploratory Associations with Epilepsy Onset and Cortical Tuber Burden by Rui Carlos Silva, Tiago S. Bara, Daniel A. do Valle, Mara L. Cordeiro (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13362418.txt.
Description
Rui Carlos Silva and colleagues describe a 2026 study of 18 children and teens in Brazil with tuberous sclerosis complex, a rare gene disorder that grows benign tumors in many organs. The team ran brain, behavior, and learning tests at one specialist center. They asked how seizure timing and the number of growths in the brain relate to learning and mood.
Nearly all of the children had epilepsy, and over half had seizures that drugs could not fully control. Autism and attention problems were common and often came together. Children whose seizures began early tended to score lower on thinking tests, and more brain growths went with more mood and behavior trouble. The team urges routine checks of learning and behavior for these children.
Catalog record
| CREATOR | Rui Carlos Silva, Tiago S. Bara, Daniel A. do Valle, Mara L. Cordeiro |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 29227 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |