Dual therapeutic interventions to optimize vancomycin exposure and reduce nephrotoxicity: a cohort study from a single center
Janice Xuanhui Li, Horng-Ruey Chua, Gladys Wei-Teng Chung, Jyoti Somani, Yi Da · 2026
Read Dual therapeutic interventions to optimize vancomycin exposure and reduce nephrotoxicity: a cohort study from a single center by Janice Xuanhui Li, Horng-Ruey Chua, Gladys Wei-Teng Chung, Jyoti Somani, Yi Da (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13361792.txt.
Description
Janice Xuanhui Li and co-authors report a 2026 study of safer dosing for the antibiotic vancomycin. High levels of the drug can injure the kidneys, a harm that raises costs and deaths in hospitals. Their quality project tried two changes at once at a single center.
First, the target low point for the drug in blood was lowered. Second, some wards piloted dosing based on the total exposure over time, not just the low point. The project group held 57 patients, against 80 in an older group run under the higher target. Over-high levels fell from 20 percent to 11 percent in the project group. Kidney injury rates were also lower, and the team tracked dose size and deaths as further checks.
Catalog record
| CREATOR | Janice Xuanhui Li, Horng-Ruey Chua, Gladys Wei-Teng Chung, Jyoti Somani, Yi Da |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 39 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |