Efficacy and Safety of Esketamine in Patients Undergoing Laparoscopic Cholecystectomy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Abdulrahman Hamad Aldousari, Hamad Alkandari, Sulaiman Alruwaished, Yousef M. F. H. Almutairi, Abdulwahab Alkandari, Shekha Alnajdi, Mohammad Alsharah, Salah Termos · 2026
Read Efficacy and Safety of Esketamine in Patients Undergoing Laparoscopic Cholecystectomy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials by Abdulrahman Hamad Aldousari, Hamad Alkandari, Sulaiman Alruwaished, Yousef M. F. H. Almutairi, Abdulwahab Alkandari, Shekha Alnajdi, Mohammad Alsharah, Salah Termos (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13361626.txt.
Description
Abdulrahman Hamad Aldousari and co-authors pooled trials of esketamine for gallbladder surgery pain in a 2026 analysis. Keyhole gallbladder removal is the standard cure for gallbladder disease, but it often leaves strong pain after surgery. Opioids remain the main treatment, yet they bring nausea and breathing problems. Esketamine blocks a pain-related receptor and might ease pain with fewer opioid side effects.
The team searched five databases through August 2025 for randomized trials of esketamine given around surgery. They combined results on pain scores, blood pressure and heart stability, recovery, and safety. Pooling small trials gives a clearer verdict on whether the drug helps and harms. Surgeons and anesthetists weighing opioid-sparing plans can use these pooled findings to decide where esketamine fits.
Catalog record
| CREATOR | Abdulrahman Hamad Aldousari, Hamad Alkandari, Sulaiman Alruwaished, Yousef M. F. H. Almutairi, Abdulwahab Alkandari, Shekha Alnajdi, Mohammad Alsharah, Salah Termos |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 35378 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |