Clinical spectrum, etiology, and treatment response in neonatal autonomic seizures: A case series
Robin M. Litten, Amy L. Patterson, Amy L. McGregor, Basanagoud Mudigoudar, Nitish Chourasia · 2023
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Description
Robin Litten, Amy Patterson, Amy McGregor, Basanagoud Mudigoudar, and Nitish Chourasia describe seizures that mimic breathing pauses in this two thousand twenty-three case series. In newborns, autonomic signs like apnea, cyanosis, and pallor rarely appear as the sole sign of seizures, and spotting them demands continuous video EEG. The authors reviewed five neonates whose primary seizure sign was apnea, examining profile, cause, and treatment response.
Video EEG confirmed ictal apnea in all five within twenty-four to forty-eight hours of symptom onset. Causes spanned structural, infectious, and genetic origins, including one infant with ANKRD11-linked KBG syndrome, in which ictal apnea had never been described. Every baby's seizures stopped with single or combined antiseizure medication. The authors urge suspecting seizures when term infants show abrupt, clustered apnea with oxygen drops, and to consider genetic testing when the cause is unclear, since early treatment works well.
Catalog record
| CREATOR | Robin M. Litten, Amy L. Patterson, Amy L. McGregor, Basanagoud Mudigoudar, Nitish Chourasia |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 21 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |