Unveiling novel susceptibility genes for sarcoidosis by a cross-tissue transcriptome-wide association study
Xiqiao Sun · 2026
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Description
Xiqiao Sun hunts for new risk genes in sarcoidosis in a 2026 study. Sarcoidosis runs in families in part, and genome scans have found immune-linked regions, but which genes those signals act through is unclear. Sun used a method that joins gene activity across many tissues with genetic risk data to name likely culprit genes.
Candidate genes from that cross-tissue scan were checked with several further methods, including a technique that mimics a natural experiment and maps of gene links to chemicals and diseases. Genes that survive all these filters earn priority for lab follow-up. The work aims to move from broad risk regions to the exact genes that drive the disease.
Catalog record
| CREATOR | Xiqiao Sun |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 37627 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |