Glycosite mapping and in situ mass spectrometry imaging of MUC2 glycopeptides via on-slide mucinase digestion
Sarah C. Lowery, Mikaela K. Ribi, Joann Chongsaritsinsuk, Isabella P. Tran, Grace Grimsley, Rachel Stubler, Keira E. Mahoney, Taryn M. Lucas, Georgia Charkoftaki, Alvaro Santos-Neto, Nissi Varki, Vasilis Vasiliou, Michael Angelo, Richard R. Drake, Stacy A. Malaker · 2026
Read Glycosite mapping and in situ mass spectrometry imaging of MUC2 glycopeptides via on-slide mucinase digestion by Sarah C. Lowery, Mikaela K. Ribi, Joann Chongsaritsinsuk, Isabella P. Tran, Grace Grimsley, Rachel Stubler, Keira E. Mahoney, Taryn M. Lucas, Georgia Charkoftaki, Alvaro Santos-Neto, Nissi Varki, Vasilis Vasiliou, Michael Angelo, Richard R. Drake, Stacy A. Malaker (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13357551.txt.
Description
Lowery and thirteen co-authors map sugar coats on a gut mucus strand right in tumor flesh in this twenty twenty-six study. Off coats on such strands may drive how a tumor grows and spreads. Past tools could not tie a coat form to its spot in the flesh.
Inside, a gut enzyme cuts the strands on the slide so their bits can be weighed. Mass maps then place each bit in the tumor while lab runs name its build. In three bowel tumors, coat forms split the tumor into clear zones by type. The lab runs read the strand's coat zone in the most depth yet seen. One rare coat swap on a sugar part was caught in the runs as well.
Catalog record
| CREATOR | Sarah C. Lowery, Mikaela K. Ribi, Joann Chongsaritsinsuk, Isabella P. Tran, Grace Grimsley, Rachel Stubler, Keira E. Mahoney, Taryn M. Lucas, Georgia Charkoftaki, Alvaro Santos-Neto, Nissi Varki, Vasilis Vasiliou, Michael Angelo, Richard R. Drake, Stacy A. Malaker |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 70 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |