Diffusion MRI of white matter alterations in chronic traumatic brain injury: a systematic review and meta-analysis☆

Yining Chen, Jessica Hoffmann, Warda T. Syeda, Remika Mito, Bradford A. Moffat · 2026

Read Diffusion MRI of white matter alterations in chronic traumatic brain injury: a systematic review and meta-analysis☆ by Yining Chen, Jessica Hoffmann, Warda T. Syeda, Remika Mito, Bradford A. Moffat (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13355731.txt.

Description

Yining Chen and co-authors pooled brain scan studies in 2026 on lasting white matter harm after traumatic brain injury. White matter carries signals between brain areas, and diffusion scans can reveal hidden damage months after injury. The team kept 27 studies of people at least three months post-injury, excluding sports and combat cases, and compared them with controls.

Scans showed weaker signal direction and freer water movement across many pathways, a sign of damaged wiring. Effects were larger after moderate to severe injury, and strongest in the corpus callosum, the bridge between brain halves. Age, sex, and scanner strength swayed results, so the authors urge tighter controls in future work.

Catalog record

CREATORYining Chen, Jessica Hoffmann, Warda T. Syeda, Remika Mito, Bradford A. Moffat
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE71967
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13355731

Browse the full library · About the Tower of Babel