Kidney Survival in Children With Steroid-Resistant Nephrotic Syndrome Treated by Rituximab
Eugene Yu-hin Chan, Irene Yuk-ying Ho, Chun-Ting Au, Ellen L.M. Yu, Andrea Angeletti, Sushmita Banerjee, Olivia Boyer, Chang-Yien Chan, Anna Francis, Gian Marco Ghiggeri, Riku Hamada, Nakysa Hooman, Luke Sydney Hopf, Mohamad Ikram I, Iftikhar Ijaz, Dmytro D. Ivanov, Hee Gyung Kang, Laura Lucchetti, · 2026
Read Kidney Survival in Children With Steroid-Resistant Nephrotic Syndrome Treated by Rituximab by Eugene Yu-hin Chan, Irene Yuk-ying Ho, Chun-Ting Au, Ellen L.M. Yu, Andrea Angeletti, Sushmita Banerjee, Olivia Boyer, Chang-Yien Chan, Anna Francis, Gian Marco Ghiggeri, Riku Hamada, Nakysa Hooman, Luke Sydney Hopf, Mohamad Ikram I, Iftikhar Ijaz, Dmytro D. Ivanov, Hee Gyung Kang, Laura Lucchetti, (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13355720.txt.
Description
Eugene Yu-hin Chan and colleagues followed kidney survival in children with steroid-resistant nephrotic syndrome after rituximab, in a 2026 international cohort study. Outcomes after rituximab in this group were unclear, so the team gathered 151 children across 23 centers in 17 countries who had failed calcineurin inhibitors. Children with genetic variants were excluded.
At rituximab start, 48 percent had normal kidney function, 31 percent had stage 2 chronic kidney disease, and 21 percent had stage 3. Nineteen percent later reached kidney failure, and overall kidney survival stood at 82.7 percent at 3 years, 75.8 percent at 5 years, and 72.3 percent at 7 years. Baseline kidney stage strongly predicted survival at 5 years, guiding family counseling.
Catalog record
| CREATOR | Eugene Yu-hin Chan, Irene Yuk-ying Ho, Chun-Ting Au, Ellen L.M. Yu, Andrea Angeletti, Sushmita Banerjee, Olivia Boyer, Chang-Yien Chan, Anna Francis, Gian Marco Ghiggeri, Riku Hamada, Nakysa Hooman, Luke Sydney Hopf, Mohamad Ikram I, Iftikhar Ijaz, Dmytro D. Ivanov, Hee Gyung Kang, Laura Lucchetti, |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 40 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |