Development of radiolabeled 111In-albumin liposomes for long-term imaging of tumors

Mohammad Ahrari, Zahra Saberi, Azam Abbasi, Jafar Rahnama Yazdi, Mahmoud Reza Jaafari, Kayvan Sadri · 2026

Read Development of radiolabeled 111In-albumin liposomes for long-term imaging of tumors by Mohammad Ahrari, Zahra Saberi, Azam Abbasi, Jafar Rahnama Yazdi, Mahmoud Reza Jaafari, Kayvan Sadri (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13350595.txt.

Description

Ahrari, Saberi, Abbasi and colleagues built a long-lasting imaging agent for tumours in 2026. They filled PEGylated liposomes with albumin, labelled them with indium-111, and tested the particles in mice carrying colon tumours.

The liposomes measured about 130 nanometres and kept their albumin load stable for at least 96 hours in serum. In the mice they gathered in kidney, liver, spleen and tumour sites, staying at high levels there even as blood levels cleared. Gamma camera images showed the same hot spots, confirming the agent stayed put in tumours. The team sees it as a clinically usable tool for long-term tumour imaging.

Catalog record

CREATORMohammad Ahrari, Zahra Saberi, Azam Abbasi, Jafar Rahnama Yazdi, Mahmoud Reza Jaafari, Kayvan Sadri
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE40 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13350595

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