Clinical application of targeted next-generation sequencing in detecting organ/space surgical site infection in patients following biliary-pancreatic surgery
Yifei Yang, Rong Jiang, Yichen Duan, Zhiang Wang, Yucheng Xu, Neng Tang, Yudong Qiu, Liang Mao, Xu Fu · 2026
Read Clinical application of targeted next-generation sequencing in detecting organ/space surgical site infection in patients following biliary-pancreatic surgery by Yifei Yang, Rong Jiang, Yichen Duan, Zhiang Wang, Yucheng Xu, Neng Tang, Yudong Qiu, Liang Mao, Xu Fu (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13350536.txt.
Description
Yifei Yang and co-authors tested targeted gene sequencing for deep infections after bile duct and pancreas surgery in a 2026 retrospective study. Among 73 patients operated between January and June 2025, 27 developed organ-space infections, a severe complication needing fast, exact diagnosis.
Drainage fluid was checked by both sequencing and standard culture. Sequencing found germs in 52.1 percent of samples against 39.7 percent, with sensitivity of 92.6 versus 66.7 percent, and answers came in about 28 hours instead of 109. It also named more species, 23 against 12. Older age and prior bile drainage raised infection risk. Speed like that can steer antibiotics days earlier.
Catalog record
| CREATOR | Yifei Yang, Rong Jiang, Yichen Duan, Zhiang Wang, Yucheng Xu, Neng Tang, Yudong Qiu, Liang Mao, Xu Fu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 34000 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |