Mediastinal adipose tissue as an active player in cardiovascular disease: a multimodality imaging narrative review
Lorenza Cananzi, Federico Greco, Andrea Buoso, Caterina Bernetti, Luca Pugliese, Gianfranco Di Gennaro, Bruno Beomonte Zobel, Carlo Augusto Mallio · 2026
Read Mediastinal adipose tissue as an active player in cardiovascular disease: a multimodality imaging narrative review by Lorenza Cananzi, Federico Greco, Andrea Buoso, Caterina Bernetti, Luca Pugliese, Gianfranco Di Gennaro, Bruno Beomonte Zobel, Carlo Augusto Mallio (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13349981.txt.
Description
Lorenza Cananzi and colleagues reviewed in 2026 mediastinal fat as an active player in cardiovascular disease, moving beyond the view of fat as inert padding. Several distinct depots, including epicardial, pericoronary, pericardial, and paracardial fat, ring the heart and major vessels and actively shape cardiovascular pathophysiology.
Under healthy conditions, these compartments support and protect the heart, but in disease they release inflammatory and metabolic signals that promote atherosclerosis, arrhythmia, and dysfunction. Multimodality imaging, from CT and MRI to echocardiography and PET, can now measure each depot separately. The review shows how imaging fat depots could refine risk prediction and open new targets for prevention and treatment.
Catalog record
| CREATOR | Lorenza Cananzi, Federico Greco, Andrea Buoso, Caterina Bernetti, Luca Pugliese, Gianfranco Di Gennaro, Bruno Beomonte Zobel, Carlo Augusto Mallio |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 56 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |