Complement as a driver of immune–vascular heterogeneity across preeclampsia subtypes: toward a precision medicine framework
Yafei Ge, Ting Gao · 2026
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Description
Yafei Ge and Ting Gao reviewed the complement system in preeclampsia in 2026. They argue it helps explain why this pregnancy disorder takes such varied forms. Preeclampsia is a major cause of illness and death for mothers and babies worldwide.
Complement is part of the immune defence system. It must stay tightly controlled for a healthy placenta to form. The authors describe distinct patterns by subtype. One pathway dominates in early disease driven by placental failure. Another runs at a low level with metabolic disease. Faulty control defines a severe group that overlaps with vessel clotting disorders. Matching these patterns to subtypes could guide targeted care instead of one-size treatment.
Catalog record
| CREATOR | Yafei Ge, Ting Gao |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 47181 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |