Artificial intelligence in membranous nephropathy: transforming clinical management toward precision medicine

Lei Hua, Cuijie Zhao, Zhenhua Yuan, Hang Su, Mingyang Cai, Xianqing Ren · 2026

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Description

Lei Hua and colleagues review how artificial intelligence could sharpen care for membranous kidney disease, in a review from 2026. The disease is the top cause of primary nephrotic syndrome in adults yet swings from quiet remission to kidney failure. While biopsy and a single antibody marker poorly forecast each path, pushing doctors toward trial-and-error immune drugs.

Uses span automated tissue measuring, scan-plus-blood models that may skip biopsy, drug choice models pitting rituximab against cyclophosphamide, and living patient models fed by multi-omics in the survey. Siloed data, opaque models, and thin global testing are flagged as brakes, with the tools framed as aids that sharpen, not replace, clinician calls.

Catalog record

CREATORLei Hua, Cuijie Zhao, Zhenhua Yuan, Hang Su, Mingyang Cai, Xianqing Ren
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE45473
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13349771

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