Transcriptomics and functional characterization identify CYP73A16 as a key regulator of flavonoid biosynthesis in mulberry leaves
Rurou Long, Xueying Jin, Michael Ackah, Frank Kwarteng Amoako, Frank Kwekucher Ackah, Frank Kumi, Jianbin Li, Hao Wei, John Nelson Buah, Mengdi Zhao, Weiguo Zhao · 2026
Read Transcriptomics and functional characterization identify CYP73A16 as a key regulator of flavonoid biosynthesis in mulberry leaves by Rurou Long, Xueying Jin, Michael Ackah, Frank Kwarteng Amoako, Frank Kwekucher Ackah, Frank Kumi, Jianbin Li, Hao Wei, John Nelson Buah, Mengdi Zhao, Weiguo Zhao (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13348818.txt.
Description
Rurou Long and co-authors study in 2026 what makes some mulberry leaves rich in flavonoids, plant compounds valued in medicine. Two mulberry types differ a lot in these compounds, but the genes behind the gap were unknown. The team compared the two types leaf by leaf.
One type held well over a third more flavonoids than the other. Gene scans found close to two thousand genes at different levels, with fourteen tied to flavonoid making. When the team silenced one gene, called CYP73A16, the whole pathway dimmed and flavonoid levels dropped. The drop peaked nine days after silencing. The authors name this gene a key switch for the pathway, useful for breeding richer leaves.
Catalog record
| CREATOR | Rurou Long, Xueying Jin, Michael Ackah, Frank Kwarteng Amoako, Frank Kwekucher Ackah, Frank Kumi, Jianbin Li, Hao Wei, John Nelson Buah, Mengdi Zhao, Weiguo Zhao |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 58 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |